2024 Paai family thioesterase

Paai family thioesterase

Author: rsxk

August undefined, 2024

WebJun 19, 2007 · The single thioesterase domain from Bacillus halodurans forms an active enzyme with highest activity for the short-chain acyl-CoA substrates (J.K.F., M.M., and B.K. unpublished work). To evaluate the functional contributions of each thioesterase domain within Acot7, we compared the catalytic activity (against a range of fatty acyl-CoA ... WebRegulator family: CRP: Regulation mode: activator (repressor) Biological process: ... Locus tag: b1396 Name: paaI Funciton: predicted thioesterase Locus tag: b1397 Name ... Locus tag: b1398 Name: paaK Funciton: phenylacetyl-CoA ligase paaA-paaB-paaC-paaD-paaE-paaF-paaG-paaH-paaI-paaJ-paaK-97: 4.3: ATTTGTGATTTTACTTAACTAT: b1388-76: 3.6:

Structure, function, and regulation of thioesterases

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WebThioesterases are enzymes that hydrolyze thioester bonds in numerous biochemical pathways, for example in fatty acid synthesis. This work reports known functions, … WebPaaI family thioesterase 11908112 - Gene ResultOCU_RS31770 PaaI family thioesterase [] Gene provides a unified query environment for genes defined by sequence and/or in … WebThis beneficial bacterium, naturally found in our intestinal tract, has been linked with fighting cancer and staving off the onset of rot and the growth of harmful bacteria. The difference … how is scrooge an outsider to society

Structural basis for recruitment of tandem hotdog domains in ... - PNAS

WebMar 12, 2024 · Sense and Sensibility. ISSAQUAH FEB 1 – MAR 12, 2024 EVERETT MAR 17 – APR 9, 2024. By Kate Hamill, based on the novel by Jane Austen. Directed by Jes … WebJul 1, 2024 · Thioesterases are a large superfamily of enzymes that play important cellular roles. They catalyse the cleavage of thioester bonds that are present in a wide range of … how is scrooge misanthropicWebNov 4, 2015 · The TE13 thioesterase family members are PaaI type thioesterases, named for their presence in the phenylacetic acid paa gene cluster, and exhibit activity against … how is scrooge portrayed as an outsider

"WebMay 14, 2024 · He enjoys quiet downtime at home with his wife Amber, and their two kids, Autumn and Rock Richard. He has two older kids, Patrick and Emelia, from a previous … " - Paai family thioesterase

Paai family thioesterase

Webthioesterase (SaDHNA), a key enzyme in the vitamin K2 pathway. The crystallographic structure in combination with small angle X‑ray solution scattering data revealed a functional tetramer of

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WebJun 23, 2010 · Most are either PaaI or PaaD enzymes in the phenylacetic acid degradation pathway, and they are part of the paa gene cluster. 34 TE14–TE19 enzymes hydrolyze acyl-ACP thioesters, with those in TE14 and TE15 having HotDog folds, whereas the rest have α/β-hydrolase folds. WebJun 19, 2007 · Acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoA to free fatty acid and CoA and thereby regulate lipid metabolism and cellular signaling. We present a comprehensive structural and functional characterization of mouse acyl-CoA thioesterase 7 (Acot7).

Webstructural unit of this family is a monomer that consists of a ﬁve- or six-stranded -sheet that wraps around a long R-helix, reminiscent of a hotdog. The association of two subunits ... PaaI, phenylacetyl-CoA thioesterase. Biochemistry 2009, 48, 1293–1304 1293 10.1021/bi801879z CCC: $40.75 2009 American Chemical Society WebThe largest family within the hotdog-fold protein superfamily is comprised of thioesterases, principally because of the large demand for thioester hydrolysis in the cell. The prevalence of the hotdog-fold thioesterase family, in particular, suggests high evolvability, meaning that the hotdog-fold scaffold readily takes on new functions.

WebFamily and domain databases. CDD. cd03443 PaaI_thioesterase 1 hit; Gene3D. 3.10.129.10 Hotdog Thioesterase 1 hit; InterPro. View protein in InterPro; IPR029069 HotDog_dom_sf; IPR003736 PAAI_dom; IPR006683 Thioestr_dom; PANTHER. PTHR43240 1,4-DIHYDROXY-2-NAPHTHOYL-COA THIOESTERASE 1 1 hit;

WebPaaI thioesterases are members of the TE13 thioesterase family that catalyze the hydrolysis of thioester bonds between coenzyme A and phenylacetyl-CoA. In this study we … how is scrooge mcduck so oldWebDec 15, 2024 · Regulation of PaaI-type thioesterases revealed an induced fit regulatory mechanism and half-of-sites reactivity, with the binding of substrates inducing small rigid-body rearrangements of the hot dog domains that inhibit binding in two of four possible catalytic sites ( 10 ). how is scrooge portrayed in stave 1WebFamily and domain databases. CDD. cd03443 PaaI_thioesterase 1 hit; Gene3D. 3.10.129.10 Hotdog Thioesterase 1 hit; InterPro. View protein in InterPro; IPR039298 ACOT13; IPR029069 HotDog_dom_sf; IPR003736 PAAI_dom; IPR006683 Thioestr_dom; PANTHER. PTHR21660:SF1 ACYL-COENZYME A THIOESTERASE 13 1 hit; how is scrooge presented as an outsider essayWebJun 19, 2024 · The deduced encoding products of the rdm genes include four PKSs (RdmG, RdmH, RdmI, and RdmJ), five regulatory proteins (RdmA, RdmC, RdmD, RdmE and RdmF), one resistance protein RdmK, one PaaI family thioesterase (TE) RdmM, one acyl carrier protein (ACP) RdmN, one acyl-CoA synthetase RdmO, and two proteins with predicted … how is scrooge presented as an outcastWebOct 2, 2024 · PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. … how is scrooge presented as lonelyWebRegulator family: CRP: Regulation mode: activator (repressor) Biological process: Carbon catabolism: Effector: Cyclic 3',5'-AMP: Phylum: ... Locus tag: Spro_3080 Name: paaI Funciton: predicted thioesterase Locus tag: Spro_3081 Name: paaJ Funciton: acetyl-CoA acetyltransferase Locus ... how is scrooge presented as isolatedWebpaaI1 - Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. IX87_03710, AIL77770.1, PaaI … how is scrooge presented in the novella