Web浙江创伤外科 2 0 1 3年 6月第 1 8卷第 3期. Z H J J T r a u ma t i c, J u n e 2 0 1 3, V o 1 . 1 8 . N o . 3. 3 0 5 . 临床研究. C K 5/ 6、 p 6 3、 T T F一 1和n a p s i n— A在低分化非小细胞肺癌中区分鳞癌和腺癌的意义 潘黎明 周涛 【摘要】 目的探讨细胞角蛋白 5/ 6 ( c y t o k e r a t i n 5/ 6, C K5/ 6 )、 p 6 3、甲状腺转录因子 1 ... WebMay 16, 2015 · TTF-1, Napsin A, and CK7 are specific diagnostic markers for lung ADC. The TTF-1 gene is located on chromosome 14q13. The …
The utility of napsin‐A in the identification of primary …
WebSep 11, 2024 · Most lung ADCAs are immunoreactive for TTF-1 and/or napsin A, with the exception of mucinous ADCAs, which stain infrequently with these markers and instead express CK7, CK20, and/or CDX2, similar to gastrointestinal and pancreatobiliary ADCAs. 20 This overlap and lack of specificity as well as shared KRAS hotspot mutations, … WebFeb 11, 2024 · The most widely used IHC markers for pulmonary ADC include TTF-1 and Napsin A. TTF-1 is a homeodomain-containing transcription factor that is predominantly found in normal type II alveolar pneumocytes 25 that has shown high sensitivity and specificity in the immunohistochemical labeling of lung adenocarcinomas. 14,18,26,27 … ecowater of texas
3855 - Gene ResultKRT7 keratin 7 [ (human)] - National Center for ...
WebJun 12, 2024 · The MLCs were positive for E-cadherin, CK7, TTF-1, napsin-A, vimentin, and β-catenin (membrane), and negative for CK5/6, p40, p63, Synaptophysin, chromogranin A, and Cdx-2. EGFR mutation, ALK-EML4 fusion, HER 2 amplification, and PIK3CA mutation were detected in 16 cases, 2 cases, 1 case, and 1 case, respectively. WebApr 9, 2024 · NapsinA的敏感度和特异度均优于TTF-1。 3.CK7. 几乎100%的肺腺癌表达 CK7,但CK7 的特异性较低,有30%-60% 的肺鳞癌也表达CK7。TTF-1和Napsin A是目前诊断肺腺癌最优秀的抗体组合之一。在鉴别诊断中,CK7通常与TTF、NapsinA联合起来判断。 ... WebCK7, TTF-1 and napsin A are predominantly expressed in primary lung adenocarcinoma patients, with CDX-2 being inconsistently expressed. CK7 staining was notably heterogeneous, with 14.5% of all cases demonstrating conch scooter key west