Christianson dw
WebApr 1, 2008 · From Christianson DW: Science 316 :60–61 (6 April 2007). Illustration: P Huey. Reprinted with permission from AAAS. Isoprenoid coupling and cyclization reactions are catalyzed by terpenoid synthases, a.k.a. terpene synthases or isoprenoid synthases; synthases that catalyze cyclization reactions are also referred to as terpenoid cyclases. WebMay 23, 2014 · Abstract. An active-site water molecule coordinated by conserved histidine and asparagine residues seems to serve as the catalytic base in all ent-copalyl diphosphate synthases (CPSs). When these residues are substituted by alanine, the mutant CPSs produce stereochemically novel ent-8-hydroxy-CPP. Given the requisite presence of …
Christianson dw
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WebManaging and manipulating carbocations in biology: terpenoid cyclase structure and mechanism Authors C A Lesburg 1 , J M Caruthers , C M Paschall , D W Christianson Affiliation 1 Department of Structural Chemistry Schering-Plough Research Institute 2015 Galloping Hill Road Kenilworth NJ 07033-0539 USA. PMID: 9914250 WebAug 25, 2024 · Key advances in terpenoid cyclase structural and chemical biology are reviewed, focusing mainly on ter penoid cyclases and related prenyltransferases for …
WebChristianson DW, et al. HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature. 489: 313-7. PMID 22885700 DOI: … WebDavid W. Christianson Affiliations: Chemistry University of Pennsylvania, Philadelphia, PA, United States Area: structure-mechanism of hydrolytic metalloenzymes Website: http://webdev.chem.upenn.edu/chem/research/faculty.php?id=15 Google: "David Christianson" Mean distance: 7.43 S N B C P Tree Publications Similar researchers …
WebAmerican Chemical Society WebChristianson, D.W. (2024) Structural and Chemical Biology of Terpenoid Cyclases. Chem. Rev. 117, 11570-11648. Porter, N.J., Mahendran, A., Breslow, R., Christianson, D.W. (2024) Unusual Zinc Binding Mode of …
WebApr 6, 2007 · The CPPase-FPPase chimeras exhibit remarkable trends in biosynthetic versatility. For example, as the chimeras become increasingly CPPase-like and are …
WebNov 10, 2000 · Terpene synthases catalyze the first committed steps in the biosynthesis of monoterpenes, sesquiterpenes, and diterpenes. An overview is presented of the enzymology and mechanism of these terpene … prince george county md real estateWebDescription. Cornelia de Lange syndrome is a developmental disorder that affects many parts of the body. The features of this disorder vary widely among affected individuals and range from relatively mild to severe. … pleasant acres york pa employmentWebAug 1, 2006 · Christianson DW 1. Author information. Affiliations. 1 author. 1. Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 … pleasant activities and chronic painWebNational Center for Biotechnology Information pleasant and attractive 7 little wordsWebDec 12, 2003 · Kim CY, Chang JS, Doyon JB, Baird Jr TA, Fierke CA, Jain A, Christianson DW (2000) J Am Chem Soc 122:12125–12134. Article CAS Google Scholar Madder RD, Kim CY, Chandra PP, Doyon JB, Baird Jr TA, Fierke CA, Christianson DW, Voet JG, Jain A (2002) J Org Chem 67:582–584 prince george county minimum wage 2023WebSep 13, 2024 · David W Christianson 1 Affiliation 1 Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , 231 South 34th Street, … prince george county md weatherWebChristianson DW, Cox JD: Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymes. Annu Rev Biochem 1999;68: 33-57. Google Scholar Pocker Y, Stone JT: The catalytic versatility of erythrocyte carbonic anhydrase. 3. Kinetic studies of the enzyme-catalyzed hydrolysis of p-nitrophenyl acetate. Biochemistry 1967;6: 668-678. pleasant and easily remembered dan word